BDBM228353 US9555022, Example 04.21
SMILES: Fc1ccc(CNC(=O)c2ccc(cc2)-c2ccc3nc(Nc4ccc(cc4F)C(=O)N4CCOCC4)nn3c2)cc1
InChI Key: InChIKey=HCDBNLRJQKERFJ-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dual specificity protein kinase TTK (Homo sapiens (Human)) | BDBM228353 (US9555022, Example 04.21) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <1 | n/a | n/a | n/a | n/a | 7.7 | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (... | US Patent US9555022 (2017) BindingDB Entry DOI: 10.7270/Q25H7J86 | |||||||||||
More data for this Ligand-Target Pair |