null

SMILES: NCCc1cnc([nH]1)-c1cccc(Br)c1

InChI Key: InChIKey=VSKJPAMQPJDPLL-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 22863   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM22863 (2-(3-Bromophenyl)histamine | 2-[2-(3-bromophenyl)-...) Show SMILES NCCc1cnc([nH]1)-c1cccc(Br)c1 Show InChI InChI=1S/C11H12BrN3/c12-9-3-1-2-8(6-9)11-14-7-10(15-11)4-5-13/h1-3,6-7H,4-5,13H2,(H,14,15)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by PDSP Ki Database									J Pharmacol Exp Ther 305: 1104-15 (2003) Article DOI: 10.1124/jpet.103.049619 BindingDB Entry DOI: 10.7270/Q2HM5708
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM22863 (2-(3-Bromophenyl)histamine | 2-[2-(3-bromophenyl)-...) Show SMILES NCCc1cnc([nH]1)-c1cccc(Br)c1 Show InChI InChI=1S/C11H12BrN3/c12-9-3-1-2-8(6-9)11-14-7-10(15-11)4-5-13/h1-3,6-7H,4-5,13H2,(H,14,15)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	-8.51	n/a	n/a	n/a	n/a	n/a	7.4	37
Vrije Universiteit Amsterdam					Assay Description Ligand displacement assays were performed on The SK-N-MC/hH4R cell homogenates. Retained radioactivity was determined by liquid scintillation countin...				J Pharmacol Exp Ther 314: 1310-21 (2005) Article DOI: 10.1124/jpet.105.087965 BindingDB Entry DOI: 10.7270/Q2KD1W6V
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM22863 (2-(3-Bromophenyl)histamine | 2-[2-(3-bromophenyl)-...) Show SMILES NCCc1cnc([nH]1)-c1cccc(Br)c1 Show InChI InChI=1S/C11H12BrN3/c12-9-3-1-2-8(6-9)11-14-7-10(15-11)4-5-13/h1-3,6-7H,4-5,13H2,(H,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	2.22E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Curated by PDSP Ki Database									J Pharmacol Exp Ther 305: 1104-15 (2003) Article DOI: 10.1124/jpet.103.049619 BindingDB Entry DOI: 10.7270/Q2HM5708
					More data for this Ligand-Target Pair
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM22863 (2-(3-Bromophenyl)histamine | 2-[2-(3-bromophenyl)-...) Show SMILES NCCc1cnc([nH]1)-c1cccc(Br)c1 Show InChI InChI=1S/C11H12BrN3/c12-9-3-1-2-8(6-9)11-14-7-10(15-11)4-5-13/h1-3,6-7H,4-5,13H2,(H,14,15)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	0.741	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description Contractile effects antagonized by mepyramine (0.3-100 nM) against Histamine H1 receptor in guinea pig ileum				Bioorg Med Chem Lett 8: 2583-8 (1999) BindingDB Entry DOI: 10.7270/Q2G1621V
					More data for this Ligand-Target Pair
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM22863 (2-(3-Bromophenyl)histamine | 2-[2-(3-bromophenyl)-...) Show SMILES NCCc1cnc([nH]1)-c1cccc(Br)c1 Show InChI InChI=1S/C11H12BrN3/c12-9-3-1-2-8(6-9)11-14-7-10(15-11)4-5-13/h1-3,6-7H,4-5,13H2,(H,14,15)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description Compound was tested for the contractile effects antagonized by mepyramine (1-1000 nM) against Histamine H1 receptor of guinea pig aorta.				Bioorg Med Chem Lett 8: 2583-8 (1999) BindingDB Entry DOI: 10.7270/Q2G1621V
					More data for this Ligand-Target Pair
Histamine H3 receptor (GUINEA PIG)	BDBM22863 (2-(3-Bromophenyl)histamine | 2-[2-(3-bromophenyl)-...) Show SMILES NCCc1cnc([nH]1)-c1cccc(Br)c1 Show InChI InChI=1S/C11H12BrN3/c12-9-3-1-2-8(6-9)11-14-7-10(15-11)4-5-13/h1-3,6-7H,4-5,13H2,(H,14,15)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	6.31E+3	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description Compound was tested for the agonist activity against histamine H3 receptor of guinea pig ileum				Bioorg Med Chem Lett 8: 2583-8 (1999) BindingDB Entry DOI: 10.7270/Q2G1621V
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Cavia porcellus)	BDBM22863 (2-(3-Bromophenyl)histamine | 2-[2-(3-bromophenyl)-...) Show SMILES NCCc1cnc([nH]1)-c1cccc(Br)c1 Show InChI InChI=1S/C11H12BrN3/c12-9-3-1-2-8(6-9)11-14-7-10(15-11)4-5-13/h1-3,6-7H,4-5,13H2,(H,14,15)	MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	1.55E+5	n/a	n/a	n/a	n/a	n/a
Freie Universit£t Berlin Curated by ChEMBL					Assay Description Compound was tested for its agonist activity against M3-acetylcholine receptor of guinea pig ileum.				Bioorg Med Chem Lett 8: 2583-8 (1999) BindingDB Entry DOI: 10.7270/Q2G1621V
					More data for this Ligand-Target Pair