BDBM22891 3-[({2-[(diaminomethylidene)amino]-1,3-thiazol-4-yl}methyl)sulfanyl]-N'-sulfamoylpropanimidamide::Famotidine::MK 208::Pepcid::YM 11170::cid_5702160
SMILES: [#7]\[#6](-[#7])=[#7]\c1nc(-[#6]-[#16]-[#6]-[#6]-[#6](-[#7])=[#7]S([#7])(=O)=O)cs1
InChI Key: InChIKey=XUFQPHANEAPEMJ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histamine H2 receptor (Cavia porcellus (domestic guinea pig)) | BDBM22891 (3-[({2-[(diaminomethylidene)amino]-1,3-thiazol-4-y...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank PC cid PC sid UniChem Patents Similars | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hoechst Pharmaceutical Research Laboratories Curated by PDSP Ki Database | Nature 304: 65-7 (1983) Article DOI: 10.1038/304065a0 BindingDB Entry DOI: 10.7270/Q2930RN2 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H4 receptor (Homo sapiens (Human)) | BDBM22891 (3-[({2-[(diaminomethylidene)amino]-1,3-thiazol-4-y...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Amsterdam | Assay Description Ligand displacement assays were performed on The SK-N-MC/hH4R cell homogenates. Retained radioactivity was determined by liquid scintillation countin... | J Pharmacol Exp Ther 314: 1310-21 (2005) Article DOI: 10.1124/jpet.105.087965 BindingDB Entry DOI: 10.7270/Q2KD1W6V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
nuclear receptor coactivator 1 isoform 1 (Homo sapiens (Human)) | BDBM22891 (3-[({2-[(diaminomethylidene)amino]-1,3-thiazol-4-y...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | n/a | >7.94E+4 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2FT8JGV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
nuclear receptor coactivator 3 isoform a (Homo sapiens (Human)) | BDBM22891 (3-[({2-[(diaminomethylidene)amino]-1,3-thiazol-4-y...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase DrugBank PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | n/a | >7.94E+4 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center http://molscreen.florida.scripps.edu/ Center Affiliation: The ... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2707ZV7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NCOA2 protein (Homo sapiens (Human)) | BDBM22891 (3-[({2-[(diaminomethylidene)amino]-1,3-thiazol-4-y...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | n/a | >7.94E+4 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2QZ28CS | |||||||||||
More data for this Ligand-Target Pair |