BDBM229595 US9334288, 9
SMILES: C1CCc2c(C1)c(nc1sc3c(nnnc3c21)N1CCNCC1)N1CCOCC1
InChI Key: InChIKey=ZPVQONCMKZBGTB-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
beta-Glucuronidase (β-glucuronidase) (Homo sapiens (Human)) | BDBM229595 (US9334288, 9) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | US Patent | n/a | n/a | 1.17 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of North Carolina at Chapel Hill US Patent | Assay Description PNPG Assay: Two ß-glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorb... | US Patent US9334288 (2016) BindingDB Entry DOI: 10.7270/Q270809V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
beta-Glucuronidase (β-glucuronidase) (Homo sapiens (Human)) | BDBM229595 (US9334288, 9) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | US Patent | n/a | n/a | n/a | n/a | 3.58 | n/a | n/a | n/a | n/a |
The University of North Carolina at Chapel Hill US Patent | Assay Description PNPG Assay: Two ß-glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorb... | US Patent US9334288 (2016) BindingDB Entry DOI: 10.7270/Q270809V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
beta-Glucuronidase (β-glucuronidase) (Homo sapiens (Human)) | BDBM229595 (US9334288, 9) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
University of KwaZulu-Natal Curated by ChEMBL | Assay Description Inhibition of beta-glucuronidase (unknown origin) | Eur J Med Chem 187: (2020) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
beta-Glucuronidase (β-glucuronidase) (Homo sapiens (Human)) | BDBM229595 (US9334288, 9) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | US Patent | n/a | n/a | n/a | n/a | 3.41 | n/a | n/a | n/a | n/a |
The University of North Carolina at Chapel Hill US Patent | Assay Description PheG Assay: Two ß-glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorb... | US Patent US9334288 (2016) BindingDB Entry DOI: 10.7270/Q270809V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
beta-Glucuronidase (β-glucuronidase) (Homo sapiens (Human)) | BDBM229595 (US9334288, 9) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | US Patent | n/a | n/a | 0.984 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of North Carolina at Chapel Hill US Patent | Assay Description PheG Assay: Two ß-glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorb... | US Patent US9334288 (2016) BindingDB Entry DOI: 10.7270/Q270809V | |||||||||||
More data for this Ligand-Target Pair |