BDBM23027 1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]-7-(thiophen-2-yl)heptan-1-one::alpha-ketooxazole, 5a

SMILES: O=C(CCCCCCc1cccs1)c1ncc(o1)-c1ccccn1

InChI Key: InChIKey=VYGSYWKKZIMLJG-UHFFFAOYSA-N

Data: 1 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 23027   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty Acid Amide Hydrolase (Homo sapiens (Human))	BDBM23027 (1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]-7-(thiophen-2...) Show SMILES O=C(CCCCCCc1cccs1)c1ncc(o1)-c1ccccn1 Show InChI InChI=1S/C19H20N2O2S/c22-17(11-4-2-1-3-8-15-9-7-13-24-15)19-21-14-18(23-19)16-10-5-6-12-20-16/h5-7,9-10,12-14H,1-4,8,11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	4.30	-11.3	20	n/a	n/a	n/a	n/a	9.0	22
The Scripps Research Institute					Assay Description The inhibition assays were performed by incubating enzyme, 14C-labeled oleamide in reaction buffer at room temperature in the presence of three diffe...				J Med Chem 50: 3359-68 (2007) Article DOI: 10.1021/jm061414r BindingDB Entry DOI: 10.7270/Q2DR2SSH
					More data for this Ligand-Target Pair
Triacylglycerol Hydrolase (Homo sapiens (Human))	BDBM23027 (1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]-7-(thiophen-2...) Show SMILES O=C(CCCCCCc1cccs1)c1ncc(o1)-c1ccccn1 Show InChI InChI=1S/C19H20N2O2S/c22-17(11-4-2-1-3-8-15-9-7-13-24-15)19-21-14-18(23-19)16-10-5-6-12-20-16/h5-7,9-10,12-14H,1-4,8,11H2	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	25
The Scripps Research Institute					Assay Description Inhibition of TGH activity was assayed using COS-7 expressed TGH and the chromogenic substrate. IC50 values were determined from the inhibition obser...				J Med Chem 50: 3359-68 (2007) Article DOI: 10.1021/jm061414r BindingDB Entry DOI: 10.7270/Q2DR2SSH
					More data for this Ligand-Target Pair