BDBM23049 7-[3-(methylsulfanyl)phenyl]-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]heptan-1-one::alpha-ketooxazole, 5u

SMILES: CSc1cccc(CCCCCCC(=O)c2ncc(o2)-c2ccccn2)c1

InChI Key: InChIKey=ODQCXALXZCGYKU-UHFFFAOYSA-N

Data: 1 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 23049   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty Acid Amide Hydrolase (Homo sapiens (Human))	BDBM23049 (7-[3-(methylsulfanyl)phenyl]-1-[5-(pyridin-2-yl)-1...) Show SMILES CSc1cccc(CCCCCCC(=O)c2ncc(o2)-c2ccccn2)c1 Show InChI InChI=1S/C22H24N2O2S/c1-27-18-11-8-10-17(15-18)9-4-2-3-5-13-20(25)22-24-16-21(26-22)19-12-6-7-14-23-19/h6-8,10-12,14-16H,2-5,9,13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	4.20	-11.3	10	n/a	n/a	n/a	n/a	9.0	22
The Scripps Research Institute					Assay Description The inhibition assays were performed by incubating enzyme, 14C-labeled oleamide in reaction buffer at room temperature in the presence of three diffe...				J Med Chem 50: 3359-68 (2007) Article DOI: 10.1021/jm061414r BindingDB Entry DOI: 10.7270/Q2DR2SSH
					More data for this Ligand-Target Pair
Triacylglycerol Hydrolase (Homo sapiens (Human))	BDBM23049 (7-[3-(methylsulfanyl)phenyl]-1-[5-(pyridin-2-yl)-1...) Show SMILES CSc1cccc(CCCCCCC(=O)c2ncc(o2)-c2ccccn2)c1 Show InChI InChI=1S/C22H24N2O2S/c1-27-18-11-8-10-17(15-18)9-4-2-3-5-13-20(25)22-24-16-21(26-22)19-12-6-7-14-23-19/h6-8,10-12,14-16H,2-5,9,13H2,1H3	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	25
The Scripps Research Institute					Assay Description Inhibition of TGH activity was assayed using COS-7 expressed TGH and the chromogenic substrate. IC50 values were determined from the inhibition obser...				J Med Chem 50: 3359-68 (2007) Article DOI: 10.1021/jm061414r BindingDB Entry DOI: 10.7270/Q2DR2SSH
					More data for this Ligand-Target Pair