BDBM230682 US9340530, 20a::US9340530, 20b

SMILES: C[C@H]1OC(=O)[C@@]2(CC(F)(F)C(C)[C@H](\C=C\c3ccc(cn3)-c3ccccc3C#N)C12)C(O)c1cscn1

InChI Key: InChIKey=KDAQRIXGAHMQCV-XXKVWTTFSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 230682   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteinase-activated receptor 1 (Homo sapiens (Human))	BDBM230682 (US9340530, 20a | US9340530, 20b) Show SMILES C[C@H]1OC(=O)[C@@]2(CC(F)(F)C(C)[C@H](\C=C\c3ccc(cn3)-c3ccccc3C#N)C12)C(O)c1cscn1 |r| Show InChI InChI=1S/C28H25F2N3O3S/c1-16-21(10-9-20-8-7-19(12-32-20)22-6-4-3-5-18(22)11-31)24-17(2)36-26(35)27(24,14-28(16,29)30)25(34)23-13-37-15-33-23/h3-10,12-13,15-17,21,24-25,34H,14H2,1-2H3/b10-9+/t16?,17-,21+,24?,25?,27-/m1/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description HEK 293 Cells were grown in media containing DMEM, 10% FBS pen/strep/L-Glutamine and non-essential amino acids. The cells were plated in 384-well PDL...				US Patent US9340530 (2016) BindingDB Entry DOI: 10.7270/Q2K35SJH
					More data for this Ligand-Target Pair
Proteinase-activated receptor 1 (Homo sapiens (Human))	BDBM230682 (US9340530, 20a | US9340530, 20b) Show SMILES C[C@H]1OC(=O)[C@@]2(CC(F)(F)C(C)[C@H](\C=C\c3ccc(cn3)-c3ccccc3C#N)C12)C(O)c1cscn1 |r| Show InChI InChI=1S/C28H25F2N3O3S/c1-16-21(10-9-20-8-7-19(12-32-20)22-6-4-3-5-18(22)11-31)24-17(2)36-26(35)27(24,14-28(16,29)30)25(34)23-13-37-15-33-23/h3-10,12-13,15-17,21,24-25,34H,14H2,1-2H3/b10-9+/t16?,17-,21+,24?,25?,27-/m1/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description HEK 293 Cells were grown in media containing DMEM, 10% FBS pen/strep/L-Glutamine and non-essential amino acids. The cells were plated in 384-well PDL...				US Patent US9340530 (2016) BindingDB Entry DOI: 10.7270/Q2K35SJH
					More data for this Ligand-Target Pair