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BDBM23090 7-(3-nitrophenyl)-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]hept-6-yn-1-one::alpha-ketooxazole, 4ss

SMILES: [O-][N+](=O)c1cccc(c1)C#CCCCCC(=O)c1ncc(o1)-c1ccccn1

InChI Key: InChIKey=NWBFHOXUGMUSGN-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23090   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty Acid Amide Hydrolase


(Homo sapiens (Human))
BDBM23090
PNG
(7-(3-nitrophenyl)-1-[5-(pyridin-2-yl)-1,3-oxazol-2...)
Show SMILES [O-][N+](=O)c1cccc(c1)C#CCCCCC(=O)c1ncc(o1)-c1ccccn1
Show InChI InChI=1S/C21H17N3O4/c25-19(21-23-15-20(28-21)18-11-5-6-13-22-18)12-4-2-1-3-8-16-9-7-10-17(14-16)24(26)27/h5-7,9-11,13-15H,1-2,4,12H2
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MMDB

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Article
PubMed
4.80 -11.3n/an/an/an/an/an/a25



The Scripps Research Institute



Assay Description
The inhibition assays were performed by incubating enzyme, 14C-labeled oleamide in reaction buffer at room temperature in the presence of three diffe...


J Med Chem 50: 3359-68 (2007)


Article DOI: 10.1021/jm061414r
BindingDB Entry DOI: 10.7270/Q2DR2SSH
More data for this
Ligand-Target Pair