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BDBM232250 US9345742, 8

SMILES: CC[C@H](C)[C@H](NC(=O)C[C@H](N)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)COc1cccc2ccccc12)C(C)C)C(=O)N[C@@H](C(C)C)C(=O)OC

InChI Key: InChIKey=YTKTVWJKOQMELC-FNOFJKMZSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 232250   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cathepsin D


(Homo sapiens (Human))		BDBM232250
PNG
(US9345742, 8)
Show SMILES CC[C@H](C)[C@H](NC(=O)C[C@H](N)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)COc1cccc2ccccc12)C(C)C)C(=O)N[C@@H](C(C)C)C(=O)OC |r|
Show InChI InChI=1S/C40H55N5O7/c1-8-26(6)37(39(49)45-36(25(4)5)40(50)51-7)43-33(46)22-30(41)31(21-27-15-10-9-11-16-27)42-38(48)35(24(2)3)44-34(47)23-52-32-20-14-18-28-17-12-13-19-29(28)32/h9-20,24-26,30-31,35-37H,8,21-23,41H2,1-7H3,(H,42,48)(H,43,46)(H,44,47)(H,45,49)/t26-,30-,31-,35-,36-,37-/m0/s1
PDB
MMDB

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antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a 200n/an/an/an/a5.525



MERCK PATENT GMBH

US Patent


Assay Description
In order to identify modulators of cathepsin D activity, a continuous enzymatic test was carried out with a synthetic peptide which carries a fluores...

US Patent US9345742 (2016)


BindingDB Entry DOI: 10.7270/Q25Q4TZD
More data for this
Ligand-Target Pair