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SMILES: CC[C@H](C)[C@H](NC(=O)C[C@H](N)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)CC(C)C)C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)OC

InChI Key: InChIKey=VUCNXMMMHJNRET-XAOKEWJTSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 232256   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cathepsin D


(Homo sapiens (Human))		BDBM232256
PNG
(US9345742, 14)
Show SMILES CC[C@H](C)[C@H](NC(=O)C[C@H](N)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)CC(C)C)C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)OC |r|
Show InChI InChI=1S/C40H68N6O7/c1-12-27(10)36(39(51)44-32(19-24(4)5)40(52)53-11)45-34(48)22-29(41)30(21-28-16-14-13-15-17-28)43-38(50)35(26(8)9)46-37(49)31(18-23(2)3)42-33(47)20-25(6)7/h13-17,23-27,29-32,35-36H,12,18-22,41H2,1-11H3,(H,42,47)(H,43,50)(H,44,51)(H,45,48)(H,46,49)/t27-,29-,30-,31-,32-,35-,36-/m0/s1
PDB
MMDB

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KEGG

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PC cid
PC sid
UniChem
US Patent
n/an/a 160n/an/an/an/a5.525



MERCK PATENT GMBH

US Patent


Assay Description
In order to identify modulators of cathepsin D activity, a continuous enzymatic test was carried out with a synthetic peptide which carries a fluores...

US Patent US9345742 (2016)


BindingDB Entry DOI: 10.7270/Q25Q4TZD
More data for this
Ligand-Target Pair