BDBM232938 US9351973, 7::US9844553, 7

SMILES: Cc1c(nn2CCC(=O)Nc12)-c1cncc(C)c1

InChI Key: InChIKey=BMQYEDCGOCFJCK-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 232938   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2 (CYP11B2) (Homo sapiens (Human))	BDBM232938 (US9351973, 7 | US9844553, 7) Show SMILES Cc1c(nn2CCC(=O)Nc12)-c1cncc(C)c1 Show InChI InChI=1S/C13H14N4O/c1-8-5-10(7-14-6-8)12-9(2)13-15-11(18)3-4-17(13)16-12/h5-7H,3-4H2,1-2H3,(H,15,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	37
Merck Sharp & Dohme Corp. US Patent					Assay Description V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...				US Patent US9351973 (2016) BindingDB Entry DOI: 10.7270/Q2D799BC
					More data for this Ligand-Target Pair
Cytochrome P450 11B1 (Homo sapiens (Human))	BDBM232938 (US9351973, 7 | US9844553, 7) Show SMILES Cc1c(nn2CCC(=O)Nc12)-c1cncc(C)c1 Show InChI InChI=1S/C13H14N4O/c1-8-5-10(7-14-6-8)12-9(2)13-15-11(18)3-4-17(13)16-12/h5-7H,3-4H2,1-2H3,(H,15,18)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	282	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Methods for V79-Human-CYP11B2 and V79-Human-CYP11B1 Assays: V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme...				US Patent US9844553 (2017) BindingDB Entry DOI: 10.7270/Q2J67K61
					More data for this Ligand-Target Pair
Cytochrome P450 11B2 (Homo sapiens (Human))	BDBM232938 (US9351973, 7 | US9844553, 7) Show SMILES Cc1c(nn2CCC(=O)Nc12)-c1cncc(C)c1 Show InChI InChI=1S/C13H14N4O/c1-8-5-10(7-14-6-8)12-9(2)13-15-11(18)3-4-17(13)16-12/h5-7H,3-4H2,1-2H3,(H,15,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Methods for V79-Human-CYP11B2 and V79-Human-CYP11B1 Assays: V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme...				US Patent US9844553 (2017) BindingDB Entry DOI: 10.7270/Q2J67K61
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM232938 (US9351973, 7 | US9844553, 7) Show SMILES Cc1c(nn2CCC(=O)Nc12)-c1cncc(C)c1 Show InChI InChI=1S/C13H14N4O/c1-8-5-10(7-14-6-8)12-9(2)13-15-11(18)3-4-17(13)16-12/h5-7H,3-4H2,1-2H3,(H,15,18)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	282	n/a	n/a	n/a	n/a	n/a	37
Merck Sharp & Dohme Corp. US Patent					Assay Description V79 cell lines stably expressing the either the human CYP11B2 or the human CYP11B1 enzyme were generated using a standard transfection protocol. V79 ...				US Patent US9351973 (2016) BindingDB Entry DOI: 10.7270/Q2D799BC
					More data for this Ligand-Target Pair