BDBM233268 US9346786, 72

SMILES: CCN([C@@H]1CN(C[C@H]1c1ccc(Cl)c(F)c1)C(=O)C1CCN(CC1)C(=O)C1(CC1)C#N)C(=O)Oc1ccc(F)cc1

InChI Key: InChIKey=MAQKKXZKONCXCL-JYFHCDHNSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 233268   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuromedin-K receptor (Homo sapiens (Human))	BDBM233268 (US9346786, 72) Show SMILES CCN([C@@H]1CN(C[C@H]1c1ccc(Cl)c(F)c1)C(=O)C1CCN(CC1)C(=O)C1(CC1)C#N)C(=O)Oc1ccc(F)cc1 |r| Show InChI InChI=1S/C30H31ClF2N4O4/c1-2-37(29(40)41-22-6-4-21(32)5-7-22)26-17-36(16-23(26)20-3-8-24(31)25(33)15-20)27(38)19-9-13-35(14-10-19)28(39)30(18-34)11-12-30/h3-8,15,19,23,26H,2,9-14,16-17H2,1H3/t23-,26+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2	-11.0	n/a	n/a	n/a	n/a	n/a	7.4	4
Hoffmann-La Roche Inc. US Patent					Assay Description hNK3 receptor binding experiment were performed using [3H]SR142801 (Catalog No. TRK1035, specific activity: 74.0 Ci/mmol, Amersham, GE Healthcare UK ...				US Patent US9346786 (2016) BindingDB Entry DOI: 10.7270/Q20V8BPC
					More data for this Ligand-Target Pair