BDBM234238 US9346821, A-6
SMILES: NC(=N)c1ccc2cc(OC(=O)c3ccc(CN4CCC[C@@H]4C(=O)N[C@@H](CS(O)(=O)=O)C(O)=O)o3)ccc2c1
InChI Key: InChIKey=NUFFEXHLLOWDJE-VQTJNVASSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Trypsin-1 (Homo sapiens (Human)) | BDBM234238 (US9346821, A-6) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | 0.0800 | n/a | n/a | n/a | n/a | n/a | n/a | 8.0 | n/a |
AJINOMOTO CO., INC. US Patent | Assay Description Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su... | US Patent US9346821 (2016) BindingDB Entry DOI: 10.7270/Q2RB73G2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Enteropeptidase (Homo sapiens (Human)) | BDBM234238 (US9346821, A-6) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | 0.670 | n/a | n/a | n/a | n/a | n/a | n/a | 8.0 | n/a |
AJINOMOTO CO., INC. US Patent | Assay Description Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ... | US Patent US9346821 (2016) BindingDB Entry DOI: 10.7270/Q2RB73G2 | |||||||||||
More data for this Ligand-Target Pair |