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BDBM234299 Nle-ψ[P(O)(OH)O]-L-AlaOMe (7)

SMILES: CCCCC(N)P(O)(=O)O[C@@H](C)C(=O)OC

InChI Key: InChIKey=BXSPAVVJHKKOFI-MBPFSUDVNA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 234299   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Leucine aminopeptidase (LAP)


(Sus scrofa (Pig))
BDBM234299
PNG
(Nle-ψ[P(O)(OH)O]-L-AlaOMe (7))
Show SMILES CCCCC(N)P(O)(=O)O[C@@H](C)C(=O)OC |r|
Show InChI InChI=1/C9H20NO5P/c1-4-5-6-8(10)16(12,13)15-7(2)9(11)14-3/h7-8H,4-6,10H2,1-3H3,(H,12,13)/t7-,8?/s2
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
2.19E+5 -4.99n/an/an/an/an/a8.425



Academy of Sciences of the Czech Republic



Assay Description
LAP was assayed in 75 mM triethanolamine hydrochloride buffer (pH = 8.4, containing 5 mM MgCl2) at 25C. The substrate (L-leucine-p-nitroanilide) was...


J Enzyme Inhib Med Chem 26: 155-61 (2011)


Article DOI: 10.3109/14756366.2010.482047
More data for this
Ligand-Target Pair