BDBM234446 N-Isobutyl oxamate
SMILES: CC(C)CNC(=O)C([O-])=O
InChI Key: InChIKey=KTICXCJIBMTSRP-UHFFFAOYSA-M
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
L-lactate:NAD+ oxidoreductase A (LDH-A4) (Mus musculus (Mouse)) | BDBM234446 (N-Isobutyl oxamate) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.00E+6 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Instituto Politécnico Nacional | Assay Description Lactate dehydrogenase activity was determined by recording the absorbance change at 340 nm produced by the oxidation of NADH. Assays were performed a... | J Enzyme Inhib Med Chem 26: 579-86 (2011) Article DOI: 10.3109/14756366.2011.566221 BindingDB Entry DOI: 10.7270/Q2R78D36 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate:NAD+ oxidoreductase C (LDH-C4) (Mus musculus (Mouse)) | BDBM234446 (N-Isobutyl oxamate) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.00E+6 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Instituto Politécnico Nacional | Assay Description Lactate dehydrogenase activity was determined by recording the absorbance change at 340 nm produced by the oxidation of NADH. Assays were performed a... | J Enzyme Inhib Med Chem 26: 579-86 (2011) Article DOI: 10.3109/14756366.2011.566221 BindingDB Entry DOI: 10.7270/Q2R78D36 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate:NAD+ oxidoreductase B (LDH-B4) (Mus musculus (Mouse)) | BDBM234446 (N-Isobutyl oxamate) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.00E+6 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Instituto Politécnico Nacional | Assay Description Lactate dehydrogenase activity was determined by recording the absorbance change at 340 nm produced by the oxidation of NADH. Assays were performed a... | J Enzyme Inhib Med Chem 26: 579-86 (2011) Article DOI: 10.3109/14756366.2011.566221 BindingDB Entry DOI: 10.7270/Q2R78D36 | |||||||||||
More data for this Ligand-Target Pair |