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BDBM234546 US9353089, 303

SMILES: COc1ccc(cc1)C1(NC(=N)N(Cc2ccccc2C)C1=O)c1ccc(OC)cc1

InChI Key: InChIKey=VNVOIFTUZUGEIL-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 234546   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Plasmepsin 2


(Plasmodium falciparum)		BDBM234546
PNG
(US9353089, 303)
Show SMILES COc1ccc(cc1)C1(NC(=N)N(Cc2ccccc2C)C1=O)c1ccc(OC)cc1
Show InChI InChI=1S/C25H25N3O3/c1-17-6-4-5-7-18(17)16-28-23(29)25(27-24(28)26,19-8-12-21(30-2)13-9-19)20-10-14-22(31-3)15-11-20/h4-15H,16H2,1-3H3,(H2,26,27)
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/a 3.10n/an/an/an/a4.525



Saint Louis University; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences

US Patent


Assay Description
Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...

US Patent US9353089 (2016)


BindingDB Entry DOI: 10.7270/Q2GQ6WP6
More data for this
Ligand-Target Pair