BDBM234716 US9353104, 4

SMILES: COc1ccc(nc1)[C@H]1C[C@@H]1COc1cc(NCc2nnc(C)s2)c(=O)n(C)n1

InChI Key: InChIKey=BOPMKVMXOOLARY-OCCSQVGLSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 234716   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 10A (PDE10A2) (Homo sapiens (Human))	BDBM234716 (US9353104, 4) Show SMILES COc1ccc(nc1)[C@H]1C[C@@H]1COc1cc(NCc2nnc(C)s2)c(=O)n(C)n1 |r| Show InChI InChI=1S/C19H22N6O3S/c1-11-22-23-18(29-11)9-21-16-7-17(24-25(2)19(16)26)28-10-12-6-14(12)15-5-4-13(27-3)8-20-15/h4-5,7-8,12,14,21H,6,9-10H2,1-3H3/t12-,14+/m1/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, Sunny...				US Patent US9353104 (2016) BindingDB Entry DOI: 10.7270/Q2ZP4517
					More data for this Ligand-Target Pair