BDBM234757 US9353104, 51

SMILES: Cc1ccc(CNc2cc(OC[C@H]3C[C@@H]3c3ccn(C)n3)nn(C)c2=O)c(C)n1

InChI Key: InChIKey=CCCDFHJNABCGQN-SJORKVTESA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 234757   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 10A (PDE10A2) (Homo sapiens (Human))	BDBM234757 (US9353104, 51) Show SMILES Cc1ccc(CNc2cc(OC[C@H]3C[C@@H]3c3ccn(C)n3)nn(C)c2=O)c(C)n1 |r| Show InChI InChI=1S/C21H26N6O2/c1-13-5-6-15(14(2)23-13)11-22-19-10-20(25-27(4)21(19)28)29-12-16-9-17(16)18-7-8-26(3)24-18/h5-8,10,16-17,22H,9,11-12H2,1-4H3/t16-,17+/m1/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, Sunny...				US Patent US9353104 (2016) BindingDB Entry DOI: 10.7270/Q2ZP4517
					More data for this Ligand-Target Pair