BDBM234761 US9353104, 55

SMILES: Cc1ccc(CNc2cc(OC[C@H]3C[C@@H]3c3ccccn3)nn(C)c2=O)c(C)n1

InChI Key: InChIKey=YLUIXFKMHUSCIE-MSOLQXFVSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 234761   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 10A (PDE10A2) (Homo sapiens (Human))	BDBM234761 (US9353104, 55) Show SMILES Cc1ccc(CNc2cc(OC[C@H]3C[C@@H]3c3ccccn3)nn(C)c2=O)c(C)n1 |r| Show InChI InChI=1S/C22H25N5O2/c1-14-7-8-16(15(2)25-14)12-24-20-11-21(26-27(3)22(20)28)29-13-17-10-18(17)19-6-4-5-9-23-19/h4-9,11,17-18,24H,10,12-13H2,1-3H3/t17-,18+/m1/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, Sunny...				US Patent US9353104 (2016) BindingDB Entry DOI: 10.7270/Q2ZP4517
					More data for this Ligand-Target Pair