BDBM234814 US9353104, 118

SMILES: Cc1cnc(CNc2cc(OC[C@H]3C[C@@H]3c3cccc(C)n3)nn(C)c2=O)s1

InChI Key: InChIKey=FOGDEYRXOPTFMK-CABCVRRESA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 234814   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 10A (PDE10A2) (Homo sapiens (Human))	BDBM234814 (US9353104, 118) Show SMILES Cc1cnc(CNc2cc(OC[C@H]3C[C@@H]3c3cccc(C)n3)nn(C)c2=O)s1 |r| Show InChI InChI=1S/C20H23N5O2S/c1-12-5-4-6-16(23-12)15-7-14(15)11-27-18-8-17(20(26)25(3)24-18)21-10-19-22-9-13(2)28-19/h4-6,8-9,14-15,21H,7,10-11H2,1-3H3/t14-,15+/m1/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, Sunny...				US Patent US9353104 (2016) BindingDB Entry DOI: 10.7270/Q2ZP4517
					More data for this Ligand-Target Pair