BDBM234819 US9353104, 124

SMILES: Cc1cnc(CNc2cc(OC[C@H]3C[C@@H]3c3ccc4CCCc4n3)nn(C)c2=O)s1

InChI Key: InChIKey=UWWZRXWBRSKMIF-CVEARBPZSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 234819   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 10A (PDE10A2) (Homo sapiens (Human))	BDBM234819 (US9353104, 124) Show SMILES Cc1cnc(CNc2cc(OC[C@H]3C[C@@H]3c3ccc4CCCc4n3)nn(C)c2=O)s1 |r| Show InChI InChI=1S/C22H25N5O2S/c1-13-10-24-21(30-13)11-23-19-9-20(26-27(2)22(19)28)29-12-15-8-16(15)18-7-6-14-4-3-5-17(14)25-18/h6-7,9-10,15-16,23H,3-5,8,11-12H2,1-2H3/t15-,16+/m1/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.00200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, Sunny...				US Patent US9353104 (2016) BindingDB Entry DOI: 10.7270/Q2ZP4517
					More data for this Ligand-Target Pair