BDBM23524 2-{3-[5-(2-chloro-4-hydroxyphenyl)thiophen-2-yl]propanamido}benzoic acid::Biaryl Anthranilide Analogue, 2f

SMILES: OC(=O)c1ccccc1NC(=O)CCc1ccc(s1)-c1ccc(O)cc1Cl

InChI Key: InChIKey=OYILCMCDPLSAFM-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23524   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM23524 (2-{3-[5-(2-chloro-4-hydroxyphenyl)thiophen-2-yl]pr...) Show SMILES OC(=O)c1ccccc1NC(=O)CCc1ccc(s1)-c1ccc(O)cc1Cl Show InChI InChI=1S/C20H16ClNO4S/c21-16-11-12(23)5-8-14(16)18-9-6-13(27-18)7-10-19(24)22-17-4-2-1-3-15(17)20(25)26/h1-6,8-9,11,23H,7,10H2,(H,22,24)(H,25,26)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	8	n/a	77	n/a	n/a	7.4	23
Merck Research Laboratories					Assay Description Membranes were incubated in binding buffer with [5, 6-3H]-niacin in the presence of test compound. After 4 hours at room temperature, reactions were ...				J Med Chem 50: 6303-6 (2007) Article DOI: 10.1021/jm700942d BindingDB Entry DOI: 10.7270/Q29S1PBG
					More data for this Ligand-Target Pair