BDBM23534 3-Carboxamide-coumarin deriv., 19::6-methyl-2-oxo-N-(propan-2-yl)-2H-chromene-3-carboxamide

SMILES: CC(C)NC(=O)c1cc2cc(C)ccc2oc1=O

InChI Key: InChIKey=HRBIDMDBDNPSIQ-UHFFFAOYSA-N

Data: 1 Other

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23534   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Factor XIIa (Homo sapiens (Human))	BDBM23534 (3-Carboxamide-coumarin deriv., 19 | 6-methyl-2-oxo...) Show SMILES CC(C)NC(=O)c1cc2cc(C)ccc2oc1=O Show InChI InChI=1S/C14H15NO3/c1-8(2)15-13(16)11-7-10-6-9(3)4-5-12(10)18-14(11)17/h4-8H,1-3H3,(H,15,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.9	22
University of Namur					Assay Description After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...				J Med Chem 51: 3077-80 (2008) Article DOI: 10.1021/jm8002697 BindingDB Entry DOI: 10.7270/Q2610XNH
					More data for this Ligand-Target Pair