BDBM23562 3-Carboxylate-coumarin deriv., 2::phenyl 6-methyl-2-oxo-2H-chromene-3-carboxylate

SMILES: Cc1ccc2oc(=O)c(cc2c1)C(=O)Oc1ccccc1

InChI Key: InChIKey=HCRNCUJVGZPUPQ-UHFFFAOYSA-N

Data: 1 Other

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23562   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Factor XIIa (Homo sapiens (Human))	BDBM23562 (3-Carboxylate-coumarin deriv., 2 | phenyl 6-methyl...) Show SMILES Cc1ccc2oc(=O)c(cc2c1)C(=O)Oc1ccccc1 Show InChI InChI=1S/C17H12O4/c1-11-7-8-15-12(9-11)10-14(17(19)21-15)16(18)20-13-5-3-2-4-6-13/h2-10H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.9	22
University of Namur					Assay Description After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...				J Med Chem 51: 3077-80 (2008) Article DOI: 10.1021/jm8002697 BindingDB Entry DOI: 10.7270/Q2610XNH
					More data for this Ligand-Target Pair