BDBM235955 US9365539, 36
SMILES: OC(CN1CCC(CC1)c1cc(nn1-c1ncccn1)-c1ccc(Cl)cc1)c1ccccc1
InChI Key: InChIKey=VSNXVFRRZXFFLD-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prolylcarboxypeptidase (PRCP) (Homo sapiens (Human)) | BDBM235955 (US9365539, 36) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.310 | n/a | n/a | n/a | n/a | 5.5 | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description The assay was run in a 384-well microliter plate at 37° C. with a total volume of 50 uL. Final assay concentrations were 0.13 nM human PrCP (CHO) or ... | US Patent US9365539 (2016) BindingDB Entry DOI: 10.7270/Q22B8WXK | |||||||||||
More data for this Ligand-Target Pair |