BDBM237234 hCA inhibitor, 5
SMILES: CCOC1Oc2c(CC)cccc2C(=O)\C1=C/Nc1ccc(cc1)S(N)(=O)=O
InChI Key: InChIKey=ZCNKMTAQKXMJRE-SFQUDFHCSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM237234 (hCA inhibitor, 5) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 286 | -8.92 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Ondokuz Mayis University | Assay Description Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ... | J Enzyme Inhib Med Chem 27: 744-7 (2012) Article DOI: 10.3109/14756366.2011.614607 BindingDB Entry DOI: 10.7270/Q2H70DQ2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 6 (CA-VI) (Homo sapiens (Human)) | BDBM237234 (hCA inhibitor, 5) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.25E+3 | -8.05 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Ondokuz Mayis University | Assay Description Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ... | J Enzyme Inhib Med Chem 27: 744-7 (2012) Article DOI: 10.3109/14756366.2011.614607 BindingDB Entry DOI: 10.7270/Q2H70DQ2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM237234 (hCA inhibitor, 5) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.43E+4 | -6.29 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Ondokuz Mayis University | Assay Description Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ... | J Enzyme Inhib Med Chem 27: 744-7 (2012) Article DOI: 10.3109/14756366.2011.614607 BindingDB Entry DOI: 10.7270/Q2H70DQ2 | |||||||||||
More data for this Ligand-Target Pair |