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BDBM237299 Ethoxzolamide (EZA)

SMILES: CCOc1ccc2nc(CS(N)(=O)=O)sc2c1

InChI Key: InChIKey=DJRLYFZDUSSRBQ-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 237299   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM237299
PNG
(Ethoxzolamide (EZA))
Show SMILES CCOc1ccc2nc(CS(N)(=O)=O)sc2c1
Show InChI InChI=1S/C10H12N2O3S2/c1-2-15-7-3-4-8-9(5-7)16-10(12-8)6-17(11,13)14/h3-5H,2,6H2,1H3,(H2,11,13,14)
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320n/an/an/an/an/an/an/an/a



Agri Ibrahim Çeçen University



Assay Description
Kinetic studies were performed using the esterase activity method, with 4-nitrophenyl acetate (NPA) as substrate.


J Enzyme Inhib Med Chem 27: 880-5 (2012)


Article DOI: 10.3109/14756366.2011.637202
BindingDB Entry DOI: 10.7270/Q2VH5MRR
More data for this
Ligand-Target Pair
Carbonic anhydrase 4


(Homo sapiens (Human))
BDBM237299
PNG
(Ethoxzolamide (EZA))
Show SMILES CCOc1ccc2nc(CS(N)(=O)=O)sc2c1
Show InChI InChI=1S/C10H12N2O3S2/c1-2-15-7-3-4-8-9(5-7)16-10(12-8)6-17(11,13)14/h3-5H,2,6H2,1H3,(H2,11,13,14)
PDB
MMDB

Reactome pathway
KEGG

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antibodypedia
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PC sid
UniChem
Article
PubMed
840n/an/an/an/an/an/an/an/a



Agri Ibrahim Çeçen University



Assay Description
Kinetic studies were performed using the esterase activity method, with 4-nitrophenyl acetate (NPA) as substrate.


J Enzyme Inhib Med Chem 27: 880-5 (2012)


Article DOI: 10.3109/14756366.2011.637202
BindingDB Entry DOI: 10.7270/Q2VH5MRR
More data for this
Ligand-Target Pair
Carbonic anhydrase 6 (CA-VI)


(Homo sapiens (Human))
BDBM237299
PNG
(Ethoxzolamide (EZA))
Show SMILES CCOc1ccc2nc(CS(N)(=O)=O)sc2c1
Show InChI InChI=1S/C10H12N2O3S2/c1-2-15-7-3-4-8-9(5-7)16-10(12-8)6-17(11,13)14/h3-5H,2,6H2,1H3,(H2,11,13,14)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
1.58E+3n/an/an/an/an/an/an/an/a



Agri Ibrahim Çeçen University



Assay Description
Kinetic studies were performed using the esterase activity method, with 4-nitrophenyl acetate (NPA) as substrate.


J Enzyme Inhib Med Chem 27: 880-5 (2012)


Article DOI: 10.3109/14756366.2011.637202
BindingDB Entry DOI: 10.7270/Q2VH5MRR
More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (Human))
BDBM237299
PNG
(Ethoxzolamide (EZA))
Show SMILES CCOc1ccc2nc(CS(N)(=O)=O)sc2c1
Show InChI InChI=1S/C10H12N2O3S2/c1-2-15-7-3-4-8-9(5-7)16-10(12-8)6-17(11,13)14/h3-5H,2,6H2,1H3,(H2,11,13,14)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

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DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
3.75E+3n/an/an/an/an/an/an/an/a



Agri Ibrahim Çeçen University



Assay Description
Kinetic studies were performed using the esterase activity method, with 4-nitrophenyl acetate (NPA) as substrate.


J Enzyme Inhib Med Chem 27: 880-5 (2012)


Article DOI: 10.3109/14756366.2011.637202
BindingDB Entry DOI: 10.7270/Q2VH5MRR
More data for this
Ligand-Target Pair