BDBM237325 US10052306, 171::rac-(3aR,5r,6aS)-2-(2-(3- fluoro-4-hydroxyphenyl)- 2-hydroxyethyl)-5-(4- fluorobenzyl)octahydro- cyclopenta[c]pyrrol-5-ol

SMILES: OC(CN1C[C@H]2C[C@](O)(Cc3ccc(F)cc3)C[C@H]2C1)c1ccc(O)c(F)c1

InChI Key: InChIKey=CMDIVHILUKWPSL-WDODAKIKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 237325   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM237325 (US10052306, 171 | rac-(3aR,5r,6aS)-2-(2-(3- fluoro...) Show SMILES OC(CN1C[C@H]2C[C@](O)(Cc3ccc(F)cc3)C[C@H]2C1)c1ccc(O)c(F)c1 |r,w:1.0| Show InChI InChI=1S/C22H25F2NO3/c23-18-4-1-14(2-5-18)8-22(28)9-16-11-25(12-17(16)10-22)13-21(27)15-3-6-20(26)19(24)7-15/h1-7,16-17,21,26-28H,8-13H2/t16-,17+,21?,22-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22.1	n/a	n/a	n/a	n/a	n/a	n/a
CADENT THERAPEUTICS, INC. US Patent					Assay Description To each well of the plate, 10 μL test compound, control (MK801) or HHnoCa buffer was added to a final concentration of 10 μM with a final c...				US Patent US10052306 (2018) BindingDB Entry DOI: 10.7270/Q20R9RD3
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