BDBM237334 (3aR,5R,6aS)-5-benzyl-2- ((R)-2-(3-fluoro-4- hydroxyphenyl)-2- hydroxyethyl)octahydro- cyclopenta[c]pyrrol-5-ol(3aR,5S,6aS)-5-benzyl-2- ((S)-2-(3-fluoro-4- hydroxyphenyl)-2- hydroxyethyl)octahydro- cyclopenta[c]pyrrol-5-ol::US10052306, 180

SMILES: O[C@@H](CN1C[C@H]2C[C@](O)(Cc3ccccc3)C[C@H]2C1)c1ccc(O)c(F)c1

InChI Key: InChIKey=ZMXDIGRWFXFDSK-UDKICSLYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 237334   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM237334 ((3aR,5R,6aS)-5-benzyl-2- ((R)-2-(3-fluoro-4- hydro...) Show SMILES O[C@@H](CN1C[C@H]2C[C@](O)(Cc3ccccc3)C[C@H]2C1)c1ccc(O)c(F)c1 |r| Show InChI InChI=1S/C22H26FNO3/c23-19-8-16(6-7-20(19)25)21(26)14-24-12-17-10-22(27,11-18(17)13-24)9-15-4-2-1-3-5-15/h1-8,17-18,21,25-27H,9-14H2/t17-,18+,21-,22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22.3	n/a	n/a	n/a	n/a	n/a	n/a
CADENT THERAPEUTICS, INC. US Patent					Assay Description To each well of the plate, 10 μL test compound, control (MK801) or HHnoCa buffer was added to a final concentration of 10 μM with a final c...				US Patent US10052306 (2018) BindingDB Entry DOI: 10.7270/Q20R9RD3
					More data for this Ligand-Target Pair