BDBM237551 US10052306, 222::rac-2-(2-(3-fluoro-4- hydroxyphenyl)-2- hydroxyethyl)-5- (thiophen-2- ylmethyl)octahydrocyclo- penta[c]pyrrol-5-ol

SMILES: OC(CN1C[C@H]2C[C@](O)(Cc3cccs3)C[C@H]2C1)c1ccc(O)c(F)c1

InChI Key: InChIKey=QZPCSULOKOSWNR-IWHGBRQISA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 237551   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM237551 (US10052306, 222 | rac-2-(2-(3-fluoro-4- hydroxyphe...) Show SMILES OC(CN1C[C@H]2C[C@](O)(Cc3cccs3)C[C@H]2C1)c1ccc(O)c(F)c1 |r,w:1.0| Show InChI InChI=1S/C20H24FNO3S/c21-17-6-13(3-4-18(17)23)19(24)12-22-10-14-7-20(25,8-15(14)11-22)9-16-2-1-5-26-16/h1-6,14-15,19,23-25H,7-12H2/t14-,15+,19?,20-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19.3	n/a	n/a	n/a	n/a	n/a	n/a
CADENT THERAPEUTICS, INC. US Patent					Assay Description To each well of the plate, 10 μL test compound, control (MK801) or HHnoCa buffer was added to a final concentration of 10 μM with a final c...				US Patent US10052306 (2018) BindingDB Entry DOI: 10.7270/Q20R9RD3
					More data for this Ligand-Target Pair