BDBM237552 US10052306, 223::rac-(3aR,5r,6aS)-5-(4- chlorobenzyl)-2-(2- hydroxy-2-(5- hydroxypyridin-2- yl)ethyl)octahydrocyclo- penta[c]pyrrol-5-ol

SMILES: OC(CN1C[C@H]2C[C@](O)(Cc3ccc(Cl)cc3)C[C@H]2C1)c1ccc(O)cn1

InChI Key: InChIKey=IZBRZTQCHRESBO-WFDYJJNTSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 237552   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM237552 (US10052306, 223 | rac-(3aR,5r,6aS)-5-(4- chloroben...) Show SMILES OC(CN1C[C@H]2C[C@](O)(Cc3ccc(Cl)cc3)C[C@H]2C1)c1ccc(O)cn1 |r,w:1.0| Show InChI InChI=1S/C21H25ClN2O3/c22-17-3-1-14(2-4-17)7-21(27)8-15-11-24(12-16(15)9-21)13-20(26)19-6-5-18(25)10-23-19/h1-6,10,15-16,20,25-27H,7-9,11-13H2/t15-,16+,20?,21-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11.5	n/a	n/a	n/a	n/a	n/a	n/a
CADENT THERAPEUTICS, INC. US Patent					Assay Description To each well of the plate, 10 μL test compound, control (MK801) or HHnoCa buffer was added to a final concentration of 10 μM with a final c...				US Patent US10052306 (2018) BindingDB Entry DOI: 10.7270/Q20R9RD3
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