BDBM237683 US10052306, 229::rac-(3aR,5r,6aS)-5-(2- fluorobenzyl)-2-(2- hydroxy-2-(4-hy- droxyphenyl)ethyl)octa- hydrocyclopenta[c] pyrrol-5-ol

SMILES: OC(CN1C[C@H]2C[C@](O)(Cc3ccccc3F)C[C@H]2C1)c1ccc(O)cc1

InChI Key: InChIKey=PWWMHMJPCISUPN-SFJHNWJUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 237683   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM237683 (US10052306, 229 | rac-(3aR,5r,6aS)-5-(2- fluoroben...) Show SMILES OC(CN1C[C@H]2C[C@](O)(Cc3ccccc3F)C[C@H]2C1)c1ccc(O)cc1 |r,w:1.0| Show InChI InChI=1S/C22H26FNO3/c23-20-4-2-1-3-16(20)9-22(27)10-17-12-24(13-18(17)11-22)14-21(26)15-5-7-19(25)8-6-15/h1-8,17-18,21,25-27H,9-14H2/t17-,18+,21?,22-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15.5	n/a	n/a	n/a	n/a	n/a	n/a
CADENT THERAPEUTICS, INC. US Patent					Assay Description To each well of the plate, 10 μL test compound, control (MK801) or HHnoCa buffer was added to a final concentration of 10 μM with a final c...				US Patent US10052306 (2018) BindingDB Entry DOI: 10.7270/Q20R9RD3
					More data for this Ligand-Target Pair