BDBM237960 US9394285, 41

SMILES: Cc1cc(ccc1C1(O)CCC1)-c1cc2c(c[nH]c2cc1Cl)C(O)=O

InChI Key: InChIKey=XATISPHWPHLPMY-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 237960   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5'-AMP-activated protein kinase Complex 1 (Homo sapiens (Human))	BDBM237960 (US9394285, 41) Show SMILES Cc1cc(ccc1C1(O)CCC1)-c1cc2c(c[nH]c2cc1Cl)C(O)=O Show InChI InChI=1S/C20H18ClNO3/c1-11-7-12(3-4-16(11)20(25)5-2-6-20)13-8-14-15(19(23)24)10-22-18(14)9-17(13)21/h3-4,7-10,22,25H,2,5-6H2,1H3,(H,23,24)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	9.60	n/a	n/a	7.5	25
Pfizer Inc. US Patent					Assay Description The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...				US Patent US9394285 (2016) BindingDB Entry DOI: 10.7270/Q2DB80Q7
					More data for this Ligand-Target Pair