BDBM238298 1-(3-aminophenyl)-4-benzoyl-5-phenyl-N-(4-sulfamoylphenyl)-1H-pyrazole-3-carboxamide (3)

SMILES: Nc1cccc(c1)-n1nc(C(=O)Nc2ccc(cc2)S(N)(=O)=O)c(C(=O)c2ccccc2)c1-c1ccccc1

InChI Key: InChIKey=VBZHZBDGBPXGNM-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 238298   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM238298 (1-(3-aminophenyl)-4-benzoyl-5-phenyl-N-(4-sulfamoy...) Show SMILES Nc1cccc(c1)-n1nc(C(=O)Nc2ccc(cc2)S(N)(=O)=O)c(C(=O)c2ccccc2)c1-c1ccccc1 Show InChI InChI=1S/C29H23N5O4S/c30-21-12-7-13-23(18-21)34-27(19-8-3-1-4-9-19)25(28(35)20-10-5-2-6-11-20)26(33-34)29(36)32-22-14-16-24(17-15-22)39(31,37)38/h1-18H,30H2,(H,32,36)(H2,31,37,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	55	-9.90	n/a	n/a	n/a	n/a	n/a	7.4	25
Dumlupinar University					Assay Description CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o...				J Enzyme Inhib Med Chem 28: 328-36 (2013) Article DOI: 10.3109/14756366.2011.651465 BindingDB Entry DOI: 10.7270/Q2V986ZJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM238298 (1-(3-aminophenyl)-4-benzoyl-5-phenyl-N-(4-sulfamoy...) Show SMILES Nc1cccc(c1)-n1nc(C(=O)Nc2ccc(cc2)S(N)(=O)=O)c(C(=O)c2ccccc2)c1-c1ccccc1 Show InChI InChI=1S/C29H23N5O4S/c30-21-12-7-13-23(18-21)34-27(19-8-3-1-4-9-19)25(28(35)20-10-5-2-6-11-20)26(33-34)29(36)32-22-14-16-24(17-15-22)39(31,37)38/h1-18H,30H2,(H,32,36)(H2,31,37,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	108	-9.50	n/a	n/a	n/a	n/a	n/a	7.4	25
Dumlupinar University					Assay Description CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o...				J Enzyme Inhib Med Chem 28: 328-36 (2013) Article DOI: 10.3109/14756366.2011.651465 BindingDB Entry DOI: 10.7270/Q2V986ZJ
					More data for this Ligand-Target Pair