BDBM238311 2-((dibenzylamino)methyl)-4,5-dimethylphenol (2e)
SMILES: Cc1cc(O)c(CN(Cc2ccccc2)Cc2ccccc2)cc1C
InChI Key: InChIKey=KNPXPQYKBWMHTC-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM238311 (2-((dibenzylamino)methyl)-4,5-dimethylphenol (2e)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.77E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Dumlupinar University | Assay Description The method for determination of Ki values is described elsewhere [Landolfi et al., J. Pharmacol. Toxicol. Methods, 38:169-172; Bülbül et al., J. Enzy... | J Enzyme Inhib Med Chem 28: 337-42 (2013) Article DOI: 10.3109/14756366.2012.693919 BindingDB Entry DOI: 10.7270/Q2KW5DZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM238311 (2-((dibenzylamino)methyl)-4,5-dimethylphenol (2e)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.40E+5 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Dumlupinar University | Assay Description Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ... | J Enzyme Inhib Med Chem 28: 337-42 (2013) Article DOI: 10.3109/14756366.2012.693919 BindingDB Entry DOI: 10.7270/Q2KW5DZ8 | |||||||||||
More data for this Ligand-Target Pair |