BDBM238861 US10052306, 300::rac-4-(2-((3aR,6aS)-5- benzylhexahydrocyclo- penta[c]pyrrol-2(1H)- yl)-1-hydroxyethyl) phenol

SMILES: OC(CN1C[C@@H]2CC(Cc3ccccc3)C[C@@H]2C1)c1ccc(O)cc1

InChI Key: InChIKey=HCJJHOOZJPOUQO-HGBKABEASA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 238861   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM238861 (US10052306, 300 | rac-4-(2-((3aR,6aS)-5- benzylhex...) Show SMILES OC(CN1C[C@@H]2CC(Cc3ccccc3)C[C@@H]2C1)c1ccc(O)cc1 |r,w:1.0,7.7| Show InChI InChI=1S/C22H27NO2/c24-21-8-6-18(7-9-21)22(25)15-23-13-19-11-17(12-20(19)14-23)10-16-4-2-1-3-5-16/h1-9,17,19-20,22,24-25H,10-15H2/t17?,19-,20+,22?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13.9	n/a	n/a	n/a	n/a	n/a	n/a
CADENT THERAPEUTICS, INC. US Patent					Assay Description To each well of the plate, 10 μL test compound, control (MK801) or HHnoCa buffer was added to a final concentration of 10 μM with a final c...				US Patent US10052306 (2018) BindingDB Entry DOI: 10.7270/Q20R9RD3
					More data for this Ligand-Target Pair