BDBM238862 US10052306, 301::rac-4-{2-[(3aR,5S,6aS)- 5-benzyl- octahydrocyclopenta[c] pyrrol-2-yl]-1- hydroxyethyl}-2- fluorophenol

SMILES: OC(CN1C[C@@H]2C[C@H](Cc3ccccc3)C[C@@H]2C1)c1ccc(O)c(F)c1

InChI Key: InChIKey=APQPXQPJQDJASQ-IZABXTHLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 238862   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM238862 (US10052306, 301 | rac-4-{2-[(3aR,5S,6aS)- 5-benzyl...) Show SMILES OC(CN1C[C@@H]2C[C@H](Cc3ccccc3)C[C@@H]2C1)c1ccc(O)c(F)c1 |r,w:1.0| Show InChI InChI=1S/C22H26FNO2/c23-20-11-17(6-7-21(20)25)22(26)14-24-12-18-9-16(10-19(18)13-24)8-15-4-2-1-3-5-15/h1-7,11,16,18-19,22,25-26H,8-10,12-14H2/t16-,18-,19+,22?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.2	n/a	n/a	n/a	n/a	n/a	n/a
CADENT THERAPEUTICS, INC. US Patent					Assay Description To each well of the plate, 10 μL test compound, control (MK801) or HHnoCa buffer was added to a final concentration of 10 μM with a final c...				US Patent US10052306 (2018) BindingDB Entry DOI: 10.7270/Q20R9RD3
					More data for this Ligand-Target Pair