BDBM238981 US9403833, 16

SMILES: Cc1c(NC(=O)c2nnn-3c2CCCc2cc(OC(F)(F)F)ccc-32)c(=O)n(C2CCCCC2)n1C

InChI Key: InChIKey=NOVSDVCDYPGXAQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 238981   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
E3 ubiquitin-protein ligase SMURF1 [420-757] (Homo sapiens (Human))	BDBM238981 (US9403833, 16) Show SMILES Cc1c(NC(=O)c2nnn-3c2CCCc2cc(OC(F)(F)F)ccc-32)c(=O)n(C2CCCCC2)n1C Show InChI InChI=1S/C24H27F3N6O3/c1-14-20(23(35)33(31(14)2)16-8-4-3-5-9-16)28-22(34)21-19-10-6-7-15-13-17(36-24(25,26)27)11-12-18(15)32(19)30-29-21/h11-13,16H,3-10H2,1-2H3,(H,28,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description For the biochemical assay panel, 50 nl of the test compounds, reference compounds and buffer/DMSO control are transferred to the respective wells of ...				US Patent US9403833 (2016) BindingDB Entry DOI: 10.7270/Q2PN94JM
					More data for this Ligand-Target Pair