null

SMILES: COc1ccc(NC(=O)NCc2ccc(cc2)C(=O)NO)cc1

InChI Key: InChIKey=ZXGFCHWWLPADDY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 239059   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 6 (Homo sapiens (Human))	BDBM239059 (US9409858, 9a) Show SMILES COc1ccc(NC(=O)NCc2ccc(cc2)C(=O)NO)cc1 Show InChI InChI=1S/C16H17N3O4/c1-23-14-8-6-13(7-9-14)18-16(21)17-10-11-2-4-12(5-3-11)15(20)19-22/h2-9,22H,10H2,1H3,(H,19,20)(H2,17,18,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.30	n/a	n/a	n/a	n/a	8.0	n/a
H. Lee Moffitt Cancer Center and Research Institute, Inc.; Board of Trustees of the University of Illinois US Patent					Assay Description HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...				US Patent US9409858 (2016) BindingDB Entry DOI: 10.7270/Q21V5CWN
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM239059 (US9409858, 9a) Show SMILES COc1ccc(NC(=O)NCc2ccc(cc2)C(=O)NO)cc1 Show InChI InChI=1S/C16H17N3O4/c1-23-14-8-6-13(7-9-14)18-16(21)17-10-11-2-4-12(5-3-11)15(20)19-22/h2-9,22H,10H2,1H3,(H,19,20)(H2,17,18,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.06E+3	n/a	n/a	n/a	n/a	8.0	n/a
H. Lee Moffitt Cancer Center and Research Institute, Inc.; Board of Trustees of the University of Illinois US Patent					Assay Description HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...				US Patent US9409858 (2016) BindingDB Entry DOI: 10.7270/Q21V5CWN
					More data for this Ligand-Target Pair