BDBM239137 US9403810, 25b
SMILES: Cc1c(onc1C(=O)Nc1c(C)n(C)n(C2CCCCC2)c1=O)[C@@H]1OC[C@@H](O1)C(C)(C)C
InChI Key: InChIKey=XDTHTVWRJCHZCK-OPAMFIHVSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
HECT-type E3 ubiquitin transferase SMURF1 (Homo sapiens (Human)) | BDBM239137 (US9403810, 25b) | PDB GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 75 | n/a | n/a | n/a | n/a | n/a | 25 |
Novartis AG US Patent | Assay Description For the biochemical assay panel, 50 nl of the test compounds, reference compounds and buffer/DMSO control are transferred to the respective wells of ... | US Patent US9403810 (2016) BindingDB Entry DOI: 10.7270/Q22V2F1F | |||||||||||
More data for this Ligand-Target Pair |