BDBM23948 1,3-dichloro-5-[(Z)-2-[4-(trifluoromethyl)phenyl]ethenyl]benzene::cis-Stilbene Derivative, 5i

SMILES: FC(F)(F)c1ccc(\C=C/c2cc(Cl)cc(Cl)c2)cc1

InChI Key: InChIKey=ISPYNXGXZRLLHM-UPHRSURJSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 23948   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aryl Hydrocarbon Receptor (AhR) (Oryctolagus cuniculus (rabbit))	BDBM23948 (1,3-dichloro-5-[(Z)-2-[4-(trifluoromethyl)phenyl]e...) Show SMILES FC(F)(F)c1ccc(\C=C/c2cc(Cl)cc(Cl)c2)cc1 Show InChI InChI=1S/C15H9Cl2F3/c16-13-7-11(8-14(17)9-13)2-1-10-3-5-12(6-4-10)15(18,19)20/h1-9H/b2-1-	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	14	-9.95	n/a	n/a	n/a	n/a	n/a	7.6	4
Institut Claudius Regaud					Assay Description Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera...				J Med Chem 48: 287-91 (2005) Article DOI: 10.1021/jm0498194 BindingDB Entry DOI: 10.7270/Q2WM1BQT
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM23948 (1,3-dichloro-5-[(Z)-2-[4-(trifluoromethyl)phenyl]e...) Show SMILES FC(F)(F)c1ccc(\C=C/c2cc(Cl)cc(Cl)c2)cc1 Show InChI InChI=1S/C15H9Cl2F3/c16-13-7-11(8-14(17)9-13)2-1-10-3-5-12(6-4-10)15(18,19)20/h1-9H/b2-1-	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut Claudius Regaud					Assay Description Cytosols from MCF-7 cells expressed ER-alpha isoform were incubated with [3H]-estradiol and eight concentrations of unlabeled test ligands. IC50 val...				J Med Chem 48: 287-91 (2005) Article DOI: 10.1021/jm0498194 BindingDB Entry DOI: 10.7270/Q2WM1BQT
					More data for this Ligand-Target Pair
Aryl hydrocarbon receptor (Homo sapiens (Human))	BDBM23948 (1,3-dichloro-5-[(Z)-2-[4-(trifluoromethyl)phenyl]e...) Show SMILES FC(F)(F)c1ccc(\C=C/c2cc(Cl)cc(Cl)c2)cc1 Show InChI InChI=1S/C15H9Cl2F3/c16-13-7-11(8-14(17)9-13)2-1-10-3-5-12(6-4-10)15(18,19)20/h1-9H/b2-1-	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article	7.14E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to aryl hydrocarbon receptor (unknown origin)				Citation and Details Article DOI: 10.1007/s00044-007-9055-2 BindingDB Entry DOI: 10.7270/Q2M32ZPJ
					More data for this Ligand-Target Pair