BDBM23949 1,3-dichloro-5-[(Z)-2-(4-methoxyphenyl)ethenyl]benzene::cis-Stilbene Derivative, 5j
SMILES: COc1ccc(\C=C/c2cc(Cl)cc(Cl)c2)cc1
InChI Key: InChIKey=YDVZIQMQLZBUKX-IHWYPQMZSA-N
Data: 5 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aryl Hydrocarbon Receptor (AhR) (Oryctolagus cuniculus (rabbit)) | BDBM23949 (1,3-dichloro-5-[(Z)-2-(4-methoxyphenyl)ethenyl]ben...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 12 | -10.0 | n/a | n/a | n/a | n/a | n/a | 7.6 | 4 |
Institut Claudius Regaud | Assay Description Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera... | J Med Chem 48: 287-91 (2005) Article DOI: 10.1021/jm0498194 BindingDB Entry DOI: 10.7270/Q2WM1BQT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aryl hydrocarbon receptor (Homo sapiens (Human)) | BDBM23949 (1,3-dichloro-5-[(Z)-2-(4-methoxyphenyl)ethenyl]ben...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to aryl hydrocarbon receptor (unknown origin) | Citation and Details Article DOI: 10.1007/s00044-009-9236-2 BindingDB Entry DOI: 10.7270/Q23X89HB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM23949 (1,3-dichloro-5-[(Z)-2-(4-methoxyphenyl)ethenyl]ben...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Claudius Regaud | Assay Description Cytosols from MCF-7 cells expressed ER-alpha isoform were incubated with [3H]-estradiol and eight concentrations of unlabeled test ligands. IC50 val... | J Med Chem 48: 287-91 (2005) Article DOI: 10.1021/jm0498194 BindingDB Entry DOI: 10.7270/Q2WM1BQT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aryl hydrocarbon receptor (Homo sapiens (Human)) | BDBM23949 (1,3-dichloro-5-[(Z)-2-(4-methoxyphenyl)ethenyl]ben...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article | 7.94E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to aryl hydrocarbon receptor (unknown origin) | Citation and Details Article DOI: 10.1007/s00044-009-9236-2 BindingDB Entry DOI: 10.7270/Q23X89HB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aryl hydrocarbon receptor (Homo sapiens (Human)) | BDBM23949 (1,3-dichloro-5-[(Z)-2-(4-methoxyphenyl)ethenyl]ben...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article | 8.34E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to aryl hydrocarbon receptor (unknown origin) | Citation and Details Article DOI: 10.1007/s00044-007-9055-2 BindingDB Entry DOI: 10.7270/Q2M32ZPJ | |||||||||||
More data for this Ligand-Target Pair |