BDBM240667 US9416127, 4::US9416127, 9
SMILES: Fc1ccc(cc1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1
InChI Key: InChIKey=XKCYWGPISGAXMK-GOSISDBHSA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Trace amine-associated receptor 1 (Mus musculus (Mouse)) | BDBM240667 (US9416127, 4 | US9416127, 9) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.400 | -13.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Hoffmann-La Roche Inc. US Patent | Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h... | US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Rattus norvegicus (Rat)) | BDBM240667 (US9416127, 4 | US9416127, 9) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Hoffmann-La Roche Inc. US Patent | Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i... | US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Mus musculus (Mouse)) | BDBM240667 (US9416127, 4 | US9416127, 9) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 2.30 | -12.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Hoffmann-La Roche Inc. US Patent | Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h... | US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 1 (Rattus norvegicus (Rat)) | BDBM240667 (US9416127, 4 | US9416127, 9) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 34.2 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Hoffmann-La Roche Inc. US Patent | Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i... | US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8 | |||||||||||
More data for this Ligand-Target Pair |