BindingDB PrimarySearch

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SMILES: NCCCC(O)=O

InChI Key: InChIKey=BTCSSZJGUNDROE-UHFFFAOYSA-N

PDB links: 79 PDB IDs match this monomer. 551 PDB IDs contain this monomer as substructures. 551 PDB IDs contain inhibitors having a similarity of 90% to this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 108 hits for monomerid = 24183
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-1 (Rattus norvegicus (Rat))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
Johannes Gutenberg-UniVersity Curated by ChEMBL					Assay Description Activity at rat wild type GABAAalpha1beta2 receptor expressed in Xenopus laevis oocytes at -60 mV by Two-Electrode voltage clamp method				J Med Chem 51: 4430-48 (2008) Article DOI: 10.1021/jm701562x BindingDB Entry DOI: 10.7270/Q2FF3S6G
Johannes Gutenberg-UniVersity Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Inhibition of Gamma-aminobutyric acid type B receptor of rat cortex				J Med Chem 38: 3287-96 (1995) BindingDB Entry DOI: 10.7270/Q2B858S0
Royal Danish School of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium- and chloride-dependent GABA transporter 1 (Rattus norvegicus)	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Budapest University of Technology and Economics Curated by ChEMBL					Assay Description H-bonding interaction between amino acid residue (Asn-137) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound				J Med Chem 47: 5620-9 (2004) Article DOI: 10.1021/jm040809c BindingDB Entry DOI: 10.7270/Q2TX3G43
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium- and chloride-dependent GABA transporter 1 (Rattus norvegicus)	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Budapest University of Technology and Economics Curated by ChEMBL					Assay Description H-bonding interaction between amino acid residue (Tyr-140) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determined				J Med Chem 47: 5620-9 (2004) Article DOI: 10.1021/jm040809c BindingDB Entry DOI: 10.7270/Q2TX3G43
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium- and chloride-dependent GABA transporter 1 (Rattus norvegicus)	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
Budapest University of Technology and Economics Curated by ChEMBL					Assay Description H-bonding interaction between amino acid residue (Ser-133) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determined				J Med Chem 47: 5620-9 (2004) Article DOI: 10.1021/jm040809c BindingDB Entry DOI: 10.7270/Q2TX3G43
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium- and chloride-dependent GABA transporter 1 (Rattus norvegicus)	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Budapest University of Technology and Economics Curated by ChEMBL					Assay Description H-bonding interaction between amino acid residue (Tyr-140) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determined				J Med Chem 47: 5620-9 (2004) Article DOI: 10.1021/jm040809c BindingDB Entry DOI: 10.7270/Q2TX3G43
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium- and chloride-dependent GABA transporter 1 (Rattus norvegicus)	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.88E+3	n/a	n/a	n/a	n/a	n/a	n/a
Budapest University of Technology and Economics Curated by ChEMBL					Assay Description H-bonding interaction between amino acid residue (Ser-133) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determined				J Med Chem 47: 5620-9 (2004) Article DOI: 10.1021/jm040809c BindingDB Entry DOI: 10.7270/Q2TX3G43
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium- and chloride-dependent GABA transporter 1 (Rattus norvegicus)	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Budapest University of Technology and Economics Curated by ChEMBL					Assay Description H-bonding interaction between amino acid residue (Tyr-140) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determined				J Med Chem 47: 5620-9 (2004) Article DOI: 10.1021/jm040809c BindingDB Entry DOI: 10.7270/Q2TX3G43
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium- and chloride-dependent GABA transporter 1 (Rattus norvegicus)	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Budapest University of Technology and Economics Curated by ChEMBL					Assay Description H-bonding interaction between amino acid residue (Asn-137) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound				J Med Chem 47: 5620-9 (2004) Article DOI: 10.1021/jm040809c BindingDB Entry DOI: 10.7270/Q2TX3G43
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium- and chloride-dependent GABA transporter 1 (Rattus norvegicus)	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Budapest University of Technology and Economics Curated by ChEMBL					Assay Description H-bonding interaction between amino acid residue (Asn-137) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound				J Med Chem 47: 5620-9 (2004) Article DOI: 10.1021/jm040809c BindingDB Entry DOI: 10.7270/Q2TX3G43
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium- and chloride-dependent GABA transporter 1 (Rattus norvegicus)	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.88E+3	n/a	n/a	n/a	n/a	n/a	n/a
Budapest University of Technology and Economics Curated by ChEMBL					Assay Description H-bonding interaction between amino acid residue (Thr-89) of Sodium- and chloride-dependent GABA transporter 1TM2 and compound				J Med Chem 47: 5620-9 (2004) Article DOI: 10.1021/jm040809c BindingDB Entry DOI: 10.7270/Q2TX3G43
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium- and chloride-dependent GABA transporter 1 (Rattus norvegicus)	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.88E+3	n/a	n/a	n/a	n/a	n/a	n/a
Budapest University of Technology and Economics Curated by ChEMBL					Assay Description H-bonding interaction between amino acid residue (Ser-133) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determined				J Med Chem 47: 5620-9 (2004) Article DOI: 10.1021/jm040809c BindingDB Entry DOI: 10.7270/Q2TX3G43
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium- and chloride-dependent GABA transporter 1 (Rattus norvegicus)	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.88E+3	n/a	n/a	n/a	n/a	n/a	n/a
Budapest University of Technology and Economics Curated by ChEMBL					Assay Description H-bonding interaction between amino acid residue (Ser-133) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determined				J Med Chem 47: 5620-9 (2004) Article DOI: 10.1021/jm040809c BindingDB Entry DOI: 10.7270/Q2TX3G43
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium- and chloride-dependent GABA transporter 1 (Rattus norvegicus)	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.88E+3	n/a	n/a	n/a	n/a	n/a	n/a
Budapest University of Technology and Economics Curated by ChEMBL					Assay Description H-bonding interaction between amino acid residue (Thr-89) of Sodium- and chloride-dependent GABA transporter 1TM2 and compound				J Med Chem 47: 5620-9 (2004) Article DOI: 10.1021/jm040809c BindingDB Entry DOI: 10.7270/Q2TX3G43
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium- and chloride-dependent GABA transporter 1 (Rattus norvegicus)	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Budapest University of Technology and Economics Curated by ChEMBL					Assay Description H-bonding interaction between amino acid residue (Asn-137) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound				J Med Chem 47: 5620-9 (2004) Article DOI: 10.1021/jm040809c BindingDB Entry DOI: 10.7270/Q2TX3G43
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium- and chloride-dependent GABA transporter 1 (Rattus norvegicus)	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.73E+3	n/a	n/a	n/a	n/a	n/a	n/a
Budapest University of Technology and Economics Curated by ChEMBL					Assay Description H-bonding interaction between amino acid residue (Tyr-140) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determined				J Med Chem 47: 5620-9 (2004) Article DOI: 10.1021/jm040809c BindingDB Entry DOI: 10.7270/Q2TX3G43
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid type B receptor subunit 1/2 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	530	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...				J Med Chem 56: 2456-65 (2013) Article DOI: 10.1021/jm301805e BindingDB Entry DOI: 10.7270/Q25T3MTS
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit rho-1 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	270	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at human GABAA rho1 receptor expressed in TSA201 cells after 1 min by FLIPR assay				J Med Chem 56: 993-1006 (2013) Article DOI: 10.1021/jm301473k BindingDB Entry DOI: 10.7270/Q2W37XMM
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium- and chloride-dependent GABA transporter 1 (Mus musculus)	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig Maximilians University at Munich Curated by ChEMBL					Assay Description Inhibition of [3H]GABA uptake at mouse GAT1 expressed in HEK293 cells after 25 mins by scintillation counting analysis				J Med Chem 56: 1323-40 (2013) Article DOI: 10.1021/jm301800j BindingDB Entry DOI: 10.7270/Q2CZ38HV
Ludwig Maximilians University at Munich Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit rho-1 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
The University of Sydney Curated by ChEMBL					Assay Description Agonist activity at GABAC rho1 receptor (unknown origin)				ACS Med Chem Lett 4: 402-7 (2013) Article DOI: 10.1021/ml300476v BindingDB Entry DOI: 10.7270/Q27H1KXG
The University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit rho-1 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	1.19E+3	n/a	n/a	n/a	n/a
The University of Sydney Curated by ChEMBL					Assay Description Agonist activity at human recombinant GABAc rho1 receptor expressed in Xenopus laevis oocytes at -60mV by two-electrode voltage clamp method				Bioorg Med Chem Lett 18: 402-4 (2008) Article DOI: 10.1016/j.bmcl.2007.10.019 BindingDB Entry DOI: 10.7270/Q2TT4RTQ
The University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium- and chloride-dependent GABA transporter 1/GABA transporter 2/GABA transporter 3/betaine transporter (Rattus norvegicus)	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro effect on GABA uptake in a crude preparation of synaptosomes from rat brain.				J Med Chem 26: 895-900 (1983) BindingDB Entry DOI: 10.7270/Q2P84CGX
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium- and chloride-dependent GABA transporter 1/GABA transporter 2/GABA transporter 3/betaine transporter (Rattus norvegicus)	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of GABA uptake in rat brain synaptic membranes				J Med Chem 28: 1612-7 (1985) BindingDB Entry DOI: 10.7270/Q2PN94NZ
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL					Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.				J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro displacement of [3H]-GABA from Gamma-aminobutyric acid type B receptor sites in rat brain membranes				Bioorg Med Chem Lett 3: 515-518 (1993) Article DOI: 10.1016/S0960-894X(01)81218-X BindingDB Entry DOI: 10.7270/Q2BR8S4N
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]baclofen from Gamma-aminobutyric acid type B receptor of rat brain membranes				J Med Chem 30: 743-6 (1987) BindingDB Entry DOI: 10.7270/Q22V2GPC
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium- and chloride-dependent GABA transporter 1/GABA transporter 2/GABA transporter 3/betaine transporter (Rattus norvegicus)	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of high affinity neuronal GABA uptake by synaptosomes of rat brain membrane				J Med Chem 25: 1157-62 (1982) BindingDB Entry DOI: 10.7270/Q2FF3VK7
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium- and chloride-dependent GABA transporter 1 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen , 2100 Copenhagen, Denmark. Curated by ChEMBL					Assay Description Inhibition of human GAT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting method				J Med Chem 60: 8834-8846 (2017) Article DOI: 10.1021/acs.jmedchem.7b00924 BindingDB Entry DOI: 10.7270/Q2M61NN1
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium- and chloride-dependent betaine transporter (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.78E+4	n/a	n/a	n/a	n/a	n/a	n/a
Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen , 2100 Copenhagen, Denmark. Curated by ChEMBL					Assay Description Inhibition of human BGT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting method				J Med Chem 60: 8834-8846 (2017) Article DOI: 10.1021/acs.jmedchem.7b00924 BindingDB Entry DOI: 10.7270/Q2M61NN1
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent betaine transporter (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.77E+4	n/a	n/a	n/a	n/a	n/a	n/a
Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen , 2100 Copenhagen, Denmark. Curated by ChEMBL					Assay Description Inhibition of human BGT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting method				J Med Chem 60: 8834-8846 (2017) Article DOI: 10.1021/acs.jmedchem.7b00924 BindingDB Entry DOI: 10.7270/Q2M61NN1
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent GABA transporter 1 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	3.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen , 2100 Copenhagen, Denmark. Curated by ChEMBL					Assay Description Inhibition of human GAT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting method				J Med Chem 60: 8834-8846 (2017) Article DOI: 10.1021/acs.jmedchem.7b00924 BindingDB Entry DOI: 10.7270/Q2M61NN1
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium- and chloride-dependent betaine transporter (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.81E+5	n/a	n/a	n/a	n/a	n/a	n/a
Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen , 2100 Copenhagen, Denmark. Curated by ChEMBL					Assay Description Inhibition of human BGT1/human GAT3 chimera C expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counti...				J Med Chem 60: 8834-8846 (2017) Article DOI: 10.1021/acs.jmedchem.7b00924 BindingDB Entry DOI: 10.7270/Q2M61NN1
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent betaine transporter (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.66E+5	n/a	n/a	n/a	n/a	n/a	n/a
Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen , 2100 Copenhagen, Denmark. Curated by ChEMBL					Assay Description Inhibition of human BGT1/human GAT3 chimera C expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counti...				J Med Chem 60: 8834-8846 (2017) Article DOI: 10.1021/acs.jmedchem.7b00924 BindingDB Entry DOI: 10.7270/Q2M61NN1
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent betaine transporter (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen , 2100 Copenhagen, Denmark. Curated by ChEMBL					Assay Description Inhibition of human BGT1/human GAT3 chimera B expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counti...				J Med Chem 60: 8834-8846 (2017) Article DOI: 10.1021/acs.jmedchem.7b00924 BindingDB Entry DOI: 10.7270/Q2M61NN1
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent betaine transporter (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen , 2100 Copenhagen, Denmark. Curated by ChEMBL					Assay Description Inhibition of human BGT1/human GAT3 chimera B expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counti...				J Med Chem 60: 8834-8846 (2017) Article DOI: 10.1021/acs.jmedchem.7b00924 BindingDB Entry DOI: 10.7270/Q2M61NN1
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent betaine transporter (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen , 2100 Copenhagen, Denmark. Curated by ChEMBL					Assay Description Inhibition of human BGT1/human GAT3 chimera D expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counti...				J Med Chem 60: 8834-8846 (2017) Article DOI: 10.1021/acs.jmedchem.7b00924 BindingDB Entry DOI: 10.7270/Q2M61NN1
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent betaine transporter (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen , 2100 Copenhagen, Denmark. Curated by ChEMBL					Assay Description Inhibition of human BGT1/human GAT3 chimera D expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counti...				J Med Chem 60: 8834-8846 (2017) Article DOI: 10.1021/acs.jmedchem.7b00924 BindingDB Entry DOI: 10.7270/Q2M61NN1
					More data for this Ligand-Target Pair
Sodium- and chloride-dependent GABA transporter 1 (Rattus norvegicus)	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	7.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians-University Munich Curated by ChEMBL					Assay Description Inhibition of mouse GAT1 expressed in HEK cells assessed as inhibition of [3H]-GABA uptake after 25 mins by liquid scintillation counting analysis				Bioorg Med Chem 21: 3363-78 (2013) Article DOI: 10.1016/j.bmc.2013.02.056 BindingDB Entry DOI: 10.7270/Q23N269C
Ludwig-Maximilians-University Munich Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium- and chloride-dependent GABA transporter 3 (Mus musculus)	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians-University Munich Curated by ChEMBL					Assay Description Inhibition of mouse GAT3 expressed in HEK cells assessed as inhibition of [3H]-GABA uptake after 25 mins by liquid scintillation counting analysis				Bioorg Med Chem 21: 3363-78 (2013) Article DOI: 10.1016/j.bmc.2013.02.056 BindingDB Entry DOI: 10.7270/Q23N269C
Ludwig-Maximilians-University Munich Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium- and chloride-dependent GABA transporter 2 (Mus musculus)	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians-University Munich Curated by ChEMBL					Assay Description Inhibition of mouse GAT2 expressed in HEK cells assessed as inhibition of [3H]-GABA uptake after 25 mins by liquid scintillation counting analysis				Bioorg Med Chem 21: 3363-78 (2013) Article DOI: 10.1016/j.bmc.2013.02.056 BindingDB Entry DOI: 10.7270/Q23N269C
Ludwig-Maximilians-University Munich Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at recombinant human GABA-A alpha1beta2gamma2S receptor transiently expressed in human tsA201 cells incubated for 30 mins and measur...				J Med Chem 62: 5797-5809 (2019) Article DOI: 10.1021/acs.jmedchem.9b00026 BindingDB Entry DOI: 10.7270/Q2D2222H
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at recombinant human GABA-A alpha1beta2gamma2S receptor transiently expressed in human tsA201 cells incubated for 30 mins and measur...				J Med Chem 62: 5797-5809 (2019) Article DOI: 10.1021/acs.jmedchem.9b00026 BindingDB Entry DOI: 10.7270/Q2D2222H
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium- and chloride-dependent GABA transporter 2 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of human GAT2 expressed in Flp-In CHO cells assessed as reduction in [3H]GABA uptake incubated for 3 mins by liquid scintillation counting...				J Med Chem 62: 5797-5809 (2019) Article DOI: 10.1021/acs.jmedchem.9b00026 BindingDB Entry DOI: 10.7270/Q2D2222H
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium- and chloride-dependent GABA transporter 3 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of human GAT3 expressed in Flp-In CHO cells assessed as reduction in [3H]GABA uptake incubated for 3 mins by liquid scintillation counting...				J Med Chem 62: 5797-5809 (2019) Article DOI: 10.1021/acs.jmedchem.9b00026 BindingDB Entry DOI: 10.7270/Q2D2222H
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-4/beta-2/gamma-2 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	3.72E+3	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at recombinant human GABA-A alpha4beta2gamma2S receptor transiently expressed in human tsA201 cells incubated for 30 mins and measur...				J Med Chem 62: 5797-5809 (2019) Article DOI: 10.1021/acs.jmedchem.9b00026 BindingDB Entry DOI: 10.7270/Q2D2222H
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit rho-1 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	339	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at recombinant human GABA-A rho-1 receptor transiently expressed in human tsA201 cells incubated for 30 mins and measured up to 90 s...				J Med Chem 62: 5797-5809 (2019) Article DOI: 10.1021/acs.jmedchem.9b00026 BindingDB Entry DOI: 10.7270/Q2D2222H
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium- and chloride-dependent GABA transporter 1 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of human GAT1 expressed in Flp-In CHO cells assessed as reduction in [3H]GABA uptake incubated for 3 mins by liquid scintillation counting...				J Med Chem 62: 5797-5809 (2019) Article DOI: 10.1021/acs.jmedchem.9b00026 BindingDB Entry DOI: 10.7270/Q2D2222H
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium- and chloride-dependent betaine transporter (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of human BGT1 expressed in Flp-In CHO cells assessed as reduction in [3H]GABA uptake incubated for 3 mins by liquid scintillation counting...				J Med Chem 62: 5797-5809 (2019) Article DOI: 10.1021/acs.jmedchem.9b00026 BindingDB Entry DOI: 10.7270/Q2D2222H
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit rho-1 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	340	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at recombinant human GABA-A rho-1 receptor transiently expressed in human tsA201 cells incubated for 30 mins and measured up to 90 s...				J Med Chem 62: 5797-5809 (2019) Article DOI: 10.1021/acs.jmedchem.9b00026 BindingDB Entry DOI: 10.7270/Q2D2222H
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-2 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	230	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at recombinant human GABA-A alpha5beta2gamma2S receptor transiently expressed in human tsA201 cells incubated for 30 mins and measur...				J Med Chem 62: 5797-5809 (2019) Article DOI: 10.1021/acs.jmedchem.9b00026 BindingDB Entry DOI: 10.7270/Q2D2222H
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)

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