BDBM24196 (3-amino-2-fluoropropyl)(methyl)phosphinic acid::3-aminopropylphosphinic derivative, 8
SMILES: CP(O)(=O)CC(F)CN
InChI Key: InChIKey=QSEZFOAWAVHOBH-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
gamma-Aminobutyric Acid Type B Receptor (Rattus norvegicus (rat)) | BDBM24196 ((3-amino-2-fluoropropyl)(methyl)phosphinic acid | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 14 | -10.6 | n/a | n/a | 23 | n/a | n/a | 7.4 | 22 |
AstraZeneca | Assay Description Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa... | J Med Chem 51: 4315-20 (2008) Article DOI: 10.1021/jm701425k BindingDB Entry DOI: 10.7270/Q2M32T2T | |||||||||||
More data for this Ligand-Target Pair |