BDBM24252 (3S)-3-amino-3-{[4-(benzyloxy)phenyl]carbamoyl}propanoic acid::Amino acid analog, 4b

SMILES: N[C@@H](CC(O)=O)C(=O)Nc1ccc(OCc2ccccc2)cc1

InChI Key: InChIKey=VTMSXGVEMJOFRJ-HNNXBMFYSA-N

Data: 1 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 24252   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A4 hydrolase (Homo sapiens (Human))	BDBM24252 ((3S)-3-amino-3-{[4-(benzyloxy)phenyl]carbamoyl}pro...) Show SMILES N[C@@H](CC(O)=O)C(=O)Nc1ccc(OCc2ccccc2)cc1 |r| Show InChI InChI=1S/C17H18N2O4/c18-15(10-16(20)21)17(22)19-13-6-8-14(9-7-13)23-11-12-4-2-1-3-5-12/h1-9,15H,10-11,18H2,(H,19,22)(H,20,21)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	7.5	22
Berlex Biosciences					Assay Description Compound potency against the peptidase activity of LTA4 hydrolase was measured by inhibition of the hydrolysis of L-alanine-p-nitroanilide to L-alani...				Bioorg Med Chem 16: 4963-83 (2008) Article DOI: 10.1016/j.bmc.2008.03.042 BindingDB Entry DOI: 10.7270/Q2BP013C
					More data for this Ligand-Target Pair				3D Structure (crystal)