BDBM242526 US9422240, 1-4

SMILES: OC1=C(C(=O)NCC([O-])=O)C(=O)N(Cc2ccc(Oc3ccc(Cl)cc3)nc2)CC1

InChI Key: InChIKey=HMMHKGLPKAQOOH-UHFFFAOYSA-M

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 242526   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 1 (Homo sapiens (Human))	BDBM242526 (US9422240, 1-4) Show SMILES OC1=C(C(=O)NCC([O-])=O)C(=O)N(Cc2ccc(Oc3ccc(Cl)cc3)nc2)CC1 |c:1| Show InChI InChI=1S/C20H18ClN3O6/c21-13-2-4-14(5-3-13)30-16-6-1-12(9-22-16)11-24-8-7-15(25)18(20(24)29)19(28)23-10-17(26)27/h1-6,9,25H,7-8,10-11H2,(H,23,28)(H,26,27)/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	7.5	n/a
TAISHO PHARMACEUTICAL CO., LTD US Patent					Assay Description The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...				US Patent US9422240 (2016) BindingDB Entry DOI: 10.7270/Q24B307K
					More data for this Ligand-Target Pair