BDBM242566 US9422240, 1-376

SMILES: CCc1ccc(Oc2ccc(CN3CCC(O)=C(C(=O)NCC(O)=O)C3=O)cn2)cc1

InChI Key: InChIKey=KKRLNLJDTLOVCD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 242566   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 1 (Homo sapiens (Human))	BDBM242566 (US9422240, 1-376) Show SMILES CCc1ccc(Oc2ccc(CN3CCC(O)=C(C(=O)NCC(O)=O)C3=O)cn2)cc1 |t:16| Show InChI InChI=1S/C22H23N3O6/c1-2-14-3-6-16(7-4-14)31-18-8-5-15(11-23-18)13-25-10-9-17(26)20(22(25)30)21(29)24-12-19(27)28/h3-8,11,26H,2,9-10,12-13H2,1H3,(H,24,29)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	7.5	n/a
TAISHO PHARMACEUTICAL CO., LTD US Patent					Assay Description The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...				US Patent US9422240 (2016) BindingDB Entry DOI: 10.7270/Q24B307K
					More data for this Ligand-Target Pair