BDBM243111 (R)-N-(1-Cyclopropyl-2-(pyrrolidin-1- yl)ethyl)-4-(5-(trifluoromethyl)-1,2,4- oxadiazol-3-yl)benzamide::US10053434, 6
SMILES: FC(F)(F)c1nc(no1)-c1ccc(cc1)C(=O)N[C@@H](CN1CCCC1)C1CC1
InChI Key: InChIKey=UHNTVGGNBPFNBL-HNNXBMFYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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HDAC4 (Homo sapiens (Human)) | BDBM243111 ((R)-N-(1-Cyclopropyl-2-(pyrrolidin-1- yl)ethyl)-4-...) | PDB GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 77 | n/a | n/a | n/a | n/a | n/a | n/a |
CHDI FOUNDATION, INC. US Patent | Assay Description 5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th... | US Patent US10053434 (2018) BindingDB Entry DOI: 10.7270/Q2MG7RJZ | |||||||||||
More data for this Ligand-Target Pair |