BDBM243176 (R)-N-(1-(6-Azaspiro[2.5]octan-6- yl)propan-2-yl)-4-(5-(trifluoromethyl)- 1,2,4-oxadiazol-3-yl)benzamide::US10053434, 12

SMILES: C[C@H](CN1CCC2(CC2)CC1)NC(=O)c1ccc(cc1)-c1noc(n1)C(F)(F)F

InChI Key: InChIKey=GUSGHJPLLXGQHZ-CYBMUJFWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 243176   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HDAC4 (Homo sapiens (Human))	BDBM243176 ((R)-N-(1-(6-Azaspiro[2.5]octan-6- yl)propan-2-yl)-...) Show SMILES C[C@H](CN1CCC2(CC2)CC1)NC(=O)c1ccc(cc1)-c1noc(n1)C(F)(F)F |r| Show InChI InChI=1S/C20H23F3N4O2/c1-13(12-27-10-8-19(6-7-19)9-11-27)24-17(28)15-4-2-14(3-5-15)16-25-18(29-26-16)20(21,22)23/h2-5,13H,6-12H2,1H3,(H,24,28)/t13-/m1/s1	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
CHDI FOUNDATION, INC. US Patent					Assay Description 5 μL of each solution of 1:20 diluted compound from above was transferred to a clear bottomed, black, 384-well assay plate using the Bravo or th...				US Patent US10053434 (2018) BindingDB Entry DOI: 10.7270/Q2MG7RJZ
					More data for this Ligand-Target Pair